Bourn Hall Clinic

Doctors Info - Publications

We have a wealth of knowledge and unrivalled experience. We carry out around 1,300 treatment cycles per year and continue to improve our success rates and range of treatments through our research.

BOOKS

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2009Preimplantation Embryo Development. In: Preimplantation Genetic DiagnosisElder K Ed Harper, CUP 2009
2007Human Preimplantation Embryo Evaluation and SelectionElder KT & Cohen JCTaylor-Francis, London
2005In Vitro Fertilization (3rd Edition)Taylor-Francis, London
2004Infections, infertility and assisted reproduction. Elder, K.T., Baker, D.J. and Ribes, J.A. Cambridge University Press
2001In Vitro Fertilization (2nd Edition)Elder KT & Dale BCambridge University Press
2000A Textbook of In Vitro Fertilization and Assisted Reproduction (2nd Edition)Brinsden PRParthenon Press, London
2000Legislation and regulation in assisted reproduction practice. Elder, K. T., Pacey, A., & Elliott, T.Worldwide Conferences in Reproductive Biology, Ladybrook Publishing, Australia
2000Micromanipulation in Assisted Reproductive Biology. Elder, K.T.,Glew, A & Elliott, TWorldwide Conferences in Reproductive Biology, Ladybrook Publishing, Australia
1999Problem solving and troubleshooting in IVFElder, K.T., & Elliott, TWorldwide Conferences in Reproductive Biology, Ladybrook Publishing, Australia
1999Blastocyst UpdateElder, K.T., & Elliott, TWorldwide Conferences in Reproductive Biology, Ladybrook Publishing, Australia
1998The use of testicular and epididymal sperm in IVF. Elder, K.T., & Elliott, TWorldwide Conferences in Reproductive Biology, Ladybrook Publishing, Australia
1997Blastocyst culture, transfer, and freezingElder, K.T., & Elliott, TWorldwide Conferences in Reproductive Biology, Ladybrook Publishing, Australia
1997In Vitro Fertilization (1st Edition)Elder KT & Dale BCambridge University Press
1992A Textbook of In Vitro Fertilization and Assisted Reproduction (1st Edition)Brinsden PR & Rainsbury PA (Eds)Parthenon Press, London
1984Edwards, R.G., Purdy J.M. & Steptoe PCImplantation of the Human EmbryoAcademic Press, London New York
1982Edwards, R.G. & Purdy J.M. Human Conception In VitroAcademic Press London New York

JOURNAL PUBLICATIONS

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Quantitative Methylation Analysis of Multiple Imprinted Gene Differentially Methylated Regions in Single Human Blastocysts by Pyrosequencing.Huntriss, J. 1*; Woodfine, K. 2; Huddlestone, J. 2; Murrell A. 2; Rutherford, A. 3; Elder, K. 4; Hemmings, K1.; Picton, H.M.1
2009Length of androgen receptor-CAG repeats in fertile and infertile Egyptian men.Badran WA, Fahmy I, Abdel-Megid WM, Elder K, Mansour R, Kent-First M.J Androl. 2009 Jul-Aug;30(4):416-25. Epub 2009 Jan 22.
2008The rates of de novo meiotic deletions and duplications causing several genomic disorders in the male germline.Turner DJ, Miretti M, Rajan D, Fiegler H, Carter NP, Blayney ML, Beck S. Hurles ME.Nature Genetics, 2008 Jan 40 (1):90-5
2008Impact of gonadotrophin stimulation for assisted reproductive technology on ovarian ageing and menopauseK Elder, T Mathews, E Kutner, E Kim, D Espenberg, M Faddy, R GosdenRBMonline 2008 16 (5):611/616
2008Responsibility and accountability of authors and co-authors.T Tulandi, K Elder, J Cohen RBMonline 2008 16 (6):763/764
2008Optimal follicle and oocyte numbers for cryopreservation of all embryos in IVF cycles at risk of OHSSGR Verwoerd, T Mathews, P BrinsdenRBMonline 2008 17 (3):312/317
2006Explaining success rates in IVF.Elder, KT (2006) Capital Doctor 50:17-18, Jan 2006
2006Infection control in the IVF laboratory.Elder, KT (2006) Embryo Talk 1,1:36-42
2006Treatment strategies in assisted reproduction for women of advanced maternal ageColin M Howles, Chung-Hoon Kim and Kay Elder (2006)Int Surg 91:S37-S54
2006Soluble HLA-G release by the human embryo: An interesting artefact ?Yves Ménézo, Kay Elder and Stephane VivilleRBMonline 13 (6), October 2006 :763-764
2006Case report: Unusual presentation of a woman with polycystic ovaries and complex endometrial pathology. K Marikinti Reproductive Biomed Online Volume 12, No 1 January 2006
2005'The presence of blood in the transfer catheter negatively influences outcome at embryo transfer'.Marikinti K, Brinsden PR.Hum Reprod. 2005 Jul; 20(7): 2029-30.
2005Implantation failures: success with quarter laser zona thinning assisted hatchingPetersen CG, Mauri AL, Baruffi RL, Oliveira JBA, Massaro FC, Elder K and Franco Jr JG (2005). RBMonline, 10(2):224-229
2004Cytoplasmic transfer in oocytes: biochemical aspectsLevy, R., Elder, K., & Menezo, Y. (2004) Human Reproduction Update 10:1-10
2004Oocyte number per live birth in IVF: were Steptoe and Edwards less wasteful?Inge, G., Brinsden, PR, Elder, KT (20040Human Reproduction, 20(3): 588-59
2004 IVF laboratory cleaning protocols.Elder, KT and Elliott, T (2004) JARG 21:63-64
2003Spindle position in ICSIAvery, S., Blayney, M. L.Human Fertility. 6 19-22.
2003Choosing the right embryo: towards single embryo transferElder, KT (2003) Journal of the Federation of Latin American Fertility Societies (FLASEF), (translated into Spanish)
2003Quality control in ARTElder, KT & Kastrop, P (2003) Journal of the Federation of Latin American Fertility Societies (FLASEF), in(translated into Spanish)
2003The role of the embryologist in ART. Elder, KT (2003) Journal of the Federation of Latin American Fertility Societies (FLASEF), (translated into Spanish)
2002Livebirth resulting from emergency TESE, after unexpected three consecutive total necrozoospermic samples on day of oocyte recovery: a case report.Marcus, S. F., Blayney, M. L., Louis, E., Burnley, A. Brinsden, P. Middle East Fertility Society Journal. 7(2) 2002;145-148.
2001A physiological replacement for polyvinylpyrrolidone (PVP) in assisted reproductive technologyBarak, Y., Menezo, Y., Veiga, A., and Elder, K., (2001)Human Fertility (2001) 4 99-103
2000Treatment by in vitro fertilisation with surrogacy: experience of one British centreBrinsden, P. R., Appleton, T. C., Murray, E., Hussein, M., Akagbosu, F., a, S. F., (2000)BMJ Volume 320 1 April 2000 Eduction and Debate
2000Has clinical practice been changed by the Human Fertilisation and Embryology Act 1990?Brinsden, P. R., (2000)Human Fertility (2000) 3, 116-120
2000The case for routine HIV screening before IVF treatment: A survey of UK IVF centre policiesMarcus S F, Avery S M, Abusheikha n, Marchus n K, and Brinsden P, (2000)Human Reproduction vol 15 no 8 pp 1657-1661 2000
1999Regulation of assisted reproductive technology The UK ExperienceBrinsden, P (1999)In Vitro Fertilization and Assisted Reproduction pp 415 – 446
1999How useful is cervical dilation in patients with cervical stenosis who are participating in an in vitro fertilization-embryo transfer program? The Bourn Hall experienceAbusheikha N., Lass A., Akagbosu, F., & Brinsden, P., (1999) Fertility and Sterility Vol 72 No 4 October 1999
1999Letters to the Editor The effect of a difficult embryo transfer on the outcome of IVFLass, L., (1999)Human Reproduction vol 14 no 9 pp 2417-2420 1999
1999The effect of a difficult embryo transfer on the outcome of IVFLass, A., Abusheikha, N., & Brinsden, P (1999)Human Reproduction 14: 2417-2420
1999Cancer Patients should be offered semen cryopreservationLass, A., (1999BMJ Vol 318 5 June 1999
1999The role of ovarian volume in reproductive medicineLass, A.and Brinsden, P (1999)Human Reproduction Update 1999 Vol 5 no 3 pp 256-266
1998A programme of semen cryopreservation for patients with malignant disease in a tertiary infertility centre: lessons from 8 years’ experienceLass, A., Akagbosu, F., Blayney, M., Avery, S., Brinsden, P., et al (1998)Human Reproduction vol 13 no 11 pp 3256-3261 1998
1998Electron Microscopy of Cryopreserved Human Spermatozoa, (Abstract),Avery, S., Morris, G.J., Blayney, M.LHuman Reproduction.13 (1): 279
1997Transrectal electroejaculation combined with in-vitro fertilization: effective treatment of anejaculatory infertility due to spinal cord injuryBrinsden, P. R., Avery, S., Marcus, S., and Macnamee, M., (1997)Human Reproduction vol 12 no 12 pp 2687-2692 1997
1996Human embryo freezing: current conditions and concernsBrinsden, P. R., (1996)Contemp Rev. Obstet. Gynaecol., 1996 Vol 8 July
1995The prediction of ectopic pregancy after in-vitro Fertilization and embryo transferMarcus, S. F., Macnamee, M., and Brinsden, P., (1995)Human Reproduction vol 10 no 8 pp 2165 – 2168
1995Diagnosis, prevention and management of ovarian hyperstimulation syndromeBrinsden, P., Balen A et al (1995)British Journal of Obs & Gynae October 1995 Vol 102 pp 767-772
1995An evaluation of the effect of Pentoxyphilline on sperm function and treatment outcome of male-factor infertility: A preliminary study.Fountain, S., Rizk, P., Avery, S., Palmer, C., Blayney, M., Mills, C., Brinsden, P.,Journal of Assisted Reproduction and Genetics 12 (10).
1995Sucessful use of Pentoxyphilline in male-factor infertility and previous failure of fertilization: A prospective randomized study.Rizk, B., Fountain, S., Avery, S., Blayney, M., Macnamee, M., Mills, C., Brinsden, PJournal of Assisted Reproduction and Genetics 12 (10).
1995Stage specific expression of cytokine and receptor messenger ribonucleic acids in human preimplantation embryos.Sharkey, A., Dellow, K., Blayney, M., Charnock-Jones, S., Smith, S.Biology of Reproduction 53 (4): 974-81
1994Tuberculous Infertility and in vitro FertilizationMarcus, S. F., Rizk, B., Fountain, S., and Brinsden, P.,American Journal of Obs & Gynae Vol 171 No 6 pp 1593 – 1596
1994Birth characteristics and perinatal outcome of babies conceived from cryopreserved embryosWada, I., Macnamee, M.C., Wick, K., Bradfield, J. M., and Brinsden, P. R. (1994)Human Reproduction vol 9 no 3 pp 543-546 1994
1994Clinical experience with highly purified FSH. Newsletter: Gonadotrophin for the 90’sBrinsden, P.R. (1994)Excerpta Medica Asia Ltd vol 1 no.1
1994High rates of pregnancy after long-term down-regulation of women with severe endometriosisMarcus, S. F., and Edwards, R. G., American Journal of Obs & Gynae Vol 171 No 3 pp 812 -817
1993Comparative trial between an ultra-short and long protocol of luteinizing hormone-releasing hormone agonist for ovarian stimulation in in-vitro FertilizationMarcus, S. F., Brinsden, P. R., Macnamee, M., Rainsbury, P. A., Elder, K. T., and Edwards, R. G., (1993)Human Reproduction vol 8 no 2 pp 238- 243 1993
1992Pronuclear, cleavage and blastocyst histories in the attempted preimplantation diagnosis of the human hydatidiform moleEdwards, R.G., Crow, J., Dale, S., Macnamee, M.C., Hartshorne, G.M., and Brinsden, P., (1992)Human Reproduction vol 7 994-998
1991Replacement of frozen-thawed embryos in artificial and natural cycles: A prospective semi-randomized studySathanandan, M., Macnamee, M.C., Rainsbury, R., Wick, K., Brinsden, P., Edwards, R.G. (1991)Human Reproduction vol 6 No 5 pp 685-687
1991Perinatal outcome and congenital malformations in in-vitro fertilization babies from the Bourn-Hallam groupRizk, B., Doyle, P., Tan, S.L., Rainsbury, P., Betts, J., Brinsden, P., and Edwards, R., (1991)Human Reproduction Vol 6 no 9 pp 1259-1264 (1991)
1991The influence of in vitro development upon post-thaw survival and implantation of cryopreserved human blastocystsHartshorne, G.M., Elder, K., Crow, J., Dyson, H., & Edwards, R.G (1991)Human Reproduction 6, 136-41
1991Intercellular Communication in the Early Human EmbryoDale, B., Elder, K et al (1991)Molecular Reproduction and Development 29:22-28 (1991)
1990Case Report Rare ectopic pregnancies after in-vitro fertilization: one unilaterla twin and four bilateral tubal pregnanciesRizk B., Morcos S., Avery S., Elder K., Brinsden P., Mason B., & Edwards R., (1990)Human Reproduction vol 5 no 8 pp 1025-1028 1990
1990Seminal plasma anti-sperm antibodies and IVF: the effect of semen sample collection into 50% serumElder, K.T., Wick, K.L. & Edwards, RG(1990) Hum. Reprod.. 5, 179-84
1990Effect of cell number at freezing upon survival and viability of cleaving embryos generated from stimulated IVF cycles. Hartshorne, G.M., Wick.K., Elder, K., & Dyson, H. (1990). Human Reprod. 5, 857-61
1990Predictive Value of LH Concentration for Obtaining a Pregnancy going to TermMacnamee, M., (1990)Extrait des Actualities Gynecologiques Vingtieme Serie
1990In vitro fertilization and development of one of two human oocytes with fused zonae pellucidae: case report. Hartshorne, G.M., Blayney, M.L., Dyson, H., Elder.K.Fertility and sterility 54 (5):947-9.
1989The role of IVF in Polycystic ovarian diseaseMacnamee, M., (1989)Research and clinical forums, 11, 89-95
1989The use of Albuminar 5 ™ as a medium supplement in clinical IVFAshwood-Smith MJ, Hollands P, & Edwards RG (1989)HR 4(6) 702-705
1989Short term luteinising hormone agonist treatment, prospective trial of a novel ovarian stimulation regimen for in vitro fertilizationMacnamee M.C., Howles C.M., Edwards RG et al. (1989)Fertil. Steril. 52 264-269
1988The Influence of stimulation regimes and luteal phase support oon the outcome of IVFMacnamee M.C., Edwards R.G., Howles C.M (1988)Human Reproduction vol 3 Supple 2 pp 43 – 52 1988
1987Pregnancies afrer IVF when high tonic LH is reduced by long-term treatment with GnRH agonistsMacnamee M.C., Howles C.M., Edwards R.G., (1987)Human Reproduction 2:569
1987Follicular development and early luteal function of conception and non-concepted cycles after human in vitro fertilizationHowles, C.M., Macnamee, M.C., & Edwards, R.G. (1987)Hum Reprod. 2, 17-21
1986Factors Affecting Survival and Implantation of Cryopreserv ed Human EmbryosCohen, J., Simons, R.S., Fehilly C B, & Edwards R G, (1986)Journal of in Vitro Fertilization and Embryo Transfer Vol 3 No 1 1986
1986Effect of high tonic levels of luteinizing hormone on outcome of in vitro fertilizationHowles, C.M., Macnamee, M.C., Edwards, R.G., Goswamy, R., , P.C. (1986) Lancet, 2, 521-522
1986Observations on 767 clinical pregnancies and 500 live births after human in vitro fertilisationSteptoe, P.C. and Edwards, R.G., Walters, D.E. (1986)Human Reproduction, 1, 89-94
1985Treatment of idiopathic infertility, cervical mucus hostility, and male infertility: artificial insemination with husband’s semen or in vitro fertilization?Hewitt, J., Cohen, J., Krishnaswamy, V., Fehilly, C. B., Steptoe, P.C., Walter,D. E., (1985)Fertility and Sterility vol 44 No 3 September 1985
1985Seminal Bacterial pathogens and in Vitro Fertilization – Short CommunicationsHewitt, J., Cohen, J., Fehilly, C B., et al (1985)Journal of in Vitro Fertilization and Embryo Transfer Vol 2 No 2 1985
1985Pregnancies following the frozen storage of expanding human blastocystsCohen, J., Simons, R.F., Edwards R G, Fehilly C B, Fishel S B. (1985)J IVF ET 2, 59-64
1985In vitro fertilisation: a treatment for male infertilityCohen, J., Edwards, R.G., Fehilly, C., Fishel, S., Hewitt, J., Purdy, J., Rowland, G., Steptoe, P.C., Webster, J. (1985)Fertil. Steril. 43, 422-32
1984Male infertility successfully treated by in vitro fertilisationCohen, J., Fehilly, C., (1984) et alLancet 1 1239
1984Factors influencing the success of in vitro fertilisation for alleviating human infertilityEdwards, R.G., Fishel. S.G., Cohen, J., Fehilly, C.B., Purdy, J.M., Steptoe, P.C., Webster, J.M. (1984)J. In Vitro Fertil & ET, 1, 3-23
1983Current Status of In-Vitro Fertilisation and Implantatnion of Human EmbryosEdwards, R G and Steptoe, P C (1983)The Lancet - Saturday 3 December 1983
1978Birth after the reimplantation of a human embryo (letter)Steptoe, P.C. and Edwards, R.G, (1978)Lancet, 2, 366
1976Reimplantation of a human embryo with subsequent tubal pregnancySteptoe, P.C. and Edwards, R.G, (1976)Lancet, 1. 880-882
1969Laparoscopy: Diagnostic and Therapeutic UsesSteptoe, P.C., (1969)Proceedings of the Royal Society of Medicine May 1969 vol 62 No 5 pp 439-441